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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED1
All Species:
18.79
Human Site:
S1129
Identified Species:
37.58
UniProt:
Q15648
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15648
NP_004765.2
1581
168478
S1129
S
S
S
S
K
L
S
S
S
M
Y
S
S
Q
G
Chimpanzee
Pan troglodytes
XP_001172395
1581
168474
S1129
S
S
S
S
K
L
S
S
S
M
Y
S
S
Q
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537654
1583
168625
S1131
S
S
S
S
K
L
S
S
S
V
Y
S
S
Q
G
Cat
Felis silvestris
Mouse
Mus musculus
Q925J9
1575
167122
G1131
S
S
S
S
K
L
S
G
S
M
Y
A
S
Q
G
Rat
Rattus norvegicus
NP_001127833
1567
166392
G1115
S
S
S
A
K
L
S
G
S
M
Y
S
S
Q
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521297
422
46589
Chicken
Gallus gallus
XP_418125
1594
169410
S1140
S
S
G
S
K
M
S
S
S
L
Y
S
S
Q
G
Frog
Xenopus laevis
Q6INP8
1570
165663
Y1120
G
S
S
G
G
G
M
Y
S
G
Q
S
G
Q
S
Zebra Danio
Brachydanio rerio
XP_700209
1694
176982
S1187
K
S
S
K
L
E
S
S
V
G
Q
G
N
I
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VP05
1475
149513
A1052
A
V
V
V
G
A
G
A
G
A
G
A
G
A
S
Honey Bee
Apis mellifera
XP_395879
1811
193227
G1355
K
S
I
F
P
S
K
G
I
G
D
R
K
S
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786427
2421
258175
S1575
V
A
S
T
S
S
T
S
S
S
S
S
V
R
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
N.A.
98
N.A.
94.4
93.9
N.A.
24.4
87.6
72.5
56.4
N.A.
22
24.4
N.A.
25.7
Protein Similarity:
100
100
N.A.
98.9
N.A.
97.1
96.5
N.A.
25.7
93.5
81.7
69
N.A.
38.9
41.1
N.A.
38.5
P-Site Identity:
100
100
N.A.
93.3
N.A.
86.6
86.6
N.A.
0
80
33.3
26.6
N.A.
0
6.6
N.A.
26.6
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
0
93.3
33.3
33.3
N.A.
20
6.6
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
9
0
9
0
9
0
9
0
17
0
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% D
% Glu:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
9
9
17
9
9
25
9
25
9
9
17
0
50
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
0
0
0
9
0
0
0
0
9
0
% I
% Lys:
17
0
0
9
50
0
9
0
0
0
0
0
9
0
0
% K
% Leu:
0
0
0
0
9
42
0
0
0
9
0
0
0
0
0
% L
% Met:
0
0
0
0
0
9
9
0
0
34
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% N
% Pro:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
17
0
0
59
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
9
0
9
0
% R
% Ser:
50
75
67
42
9
17
59
50
67
9
9
59
50
9
34
% S
% Thr:
0
0
0
9
0
0
9
0
0
0
0
0
0
0
0
% T
% Val:
9
9
9
9
0
0
0
0
9
9
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
9
0
0
50
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _